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Mutant ape may refer to:
- Silverback, a mutant ape encountered during "Defeat the dark mutants" in The Lost Frontier.
- Alpha mutant, a boss-level mutant ape encountered at the end of "Defeat the dark mutants" in The Lost Frontier.
- Franken ape, a mutant ape encountered during "Search for light eco" in The Lost Frontier.
- Hyper mutant, a boss-level mutant ape encountered at the end of "Head to the palace" in The Lost Frontier.